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Tramadol is a prescription opioid analgesic used to treat moderate to moderately severe pain. It is often prescribed when over-the-counter pain relievers are not sufficient. Tramadol works by binding to opioid receptors in the brain and spinal cord while also affecting neurotransmitters like norepinephrine and serotonin, which helps reduce the perception of pain.

Uses of Tramadol

Tramadol is commonly prescribed for:

  • Acute pain following surgery, injury, or dental procedures

  • Chronic pain conditions, such as musculoskeletal disorders

  • Moderate to severe pain that is not effectively managed by non-opioid medications

It is available in immediate-release tablets, extended-release tablets, and oral solutions, depending on the patient’s needs.

How Tramadol Works

Tramadol acts on the central nervous system to:

  • Reduce pain signal transmission

  • Alter the brain’s perception of pain

  • Provide effective relief for both acute and chronic conditions

Its dual mechanism of opioid and neurotransmitter activity differentiates it from traditional opioids, providing balanced pain control.

Dosage and Administration

  • Taken orally, usually every 4–6 hours as needed for immediate-release forms

  • Extended-release forms are used once or twice daily for chronic pain

  • Must be taken exactly as prescribed to reduce risk of overdose or dependency

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