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Tramadol is a synthetic opioid analgesic approved by the FDA for moderate to moderately severe pain in adults, functioning as a centrally acting medication that binds to mu-opioid receptors and inhibits serotonin and norepinephrine reuptake. It comes in immediate-release forms (starting at 50 mg every 4-6 hours, max 400 mg/day) and extended-release (100-300 mg once daily), with dosages adjusted for elderly patients or those with hepatic impairment to avoid risks like dependence. Unlike stronger opioids, Tramadol's dual mechanism provides effective relief for conditions like post-surgical pain or chronic osteoarthritis without immediate full opioid potency.
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Adults typically start with 50-100 mg immediate-release Tramadol every 4-6 hours as needed, not exceeding 400 mg daily, while extended-release begins at 100 mg once daily, titrated slowly. Always consult providers for personalized dosing, avoiding use in children under 12 or those with seizure history, respiratory issues, or concurrent serotonergic drugs due to risks like serotonin syndrome. Proper use minimizes side effects such as dizziness or nausea; taper gradually to prevent withdrawal.
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